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A modified protein that can deliver cancer drugs to different parts of the body; possible vaccines and therapy for tuberculosis and a host of other diseases; measuring temperatures at the nanoscale and mysterious magnetic fields in the sun are just a sample of the research that have been carried out at the Indian Institute of Science in 2013. The Indian Institute of Science (IISc), renowned for its focus on scientific and technical research is a one opf its kind autonomous research institute in India, tackling a variety of questions. They range from the atom to the universe and from bacteria to elephants. But what actually transpires within its’ majestic grey stone buildings and state of the art laboratories usually evades the public eye. Samanway 2014 is a step toward bridging this gap and remedying this situation. Students' Council is providing an interaction platform that will bring together academicians from the institute and the industry bigwigs. Part I, to take place on the 12th of April, focusses on three Divisions at IISc - Physics and Maths, Biology and Chemistry. A newsletter showcasing the research from these divisions will be released by the Students’ Council in association with Gubbi Labs, a research collective interested in popular science outreach. The newsletter will include an overview of research in each division and highlight papers recently published in highly reputed international journals. Readers will be taken through a journey from the chromosomes inside the nucleus of each cell, to how cells function synchronously together, to the larger picture of ecosystems and the biosphere. An IISc scientist was involved in the monumental discovery of the Higgs boson. A young student came up with a low cost, low power system to filter out micro particles and purify water, getting her the Gandhian Young Technological Innovations Award. Slightly modifying a naturally occurring protein, a group of chemists have designed a molecule that can deliver anti-cancer drugs to inside cells. Using clues from structures of proteins found in micro-organisms causing tuberculosis, gastro-enteritis, malaria and crop diseases, possible therapeutic drugs have been designed. Others have pushed the envelope regarding what is known about the biology of a cell - how genes are turned on and off, how proteins interact with other molecules and how we mount an immune response. Looking at patterns in the world around them and using elegant equations, mathematicians have been helping engineers design better vehicles and modelling the human brain. Neuroscientists are gaining other insights into how the brain functions - how do we recognise objects? Why do we make certain choices over others? These are the little stories that are being woven to bring you the Samanway Special Newsletter, a Gubbi Labs Initiative.