Among viruses, the Hepatitis C virus is extremely persistent – a patient sometimes cannot get rid of the virus after infection, and it remains in their cells over long periods of time. The standard HCV treatment is effective over time only in half the patients, making Hepatitis C the bane of doctors and scientists worldwide. Researchers at the Therapeutic Engineering Lab at the Department of Chemical Engineering, Indian Institute of Science, think they may know more about why the disease is persistent. Using simulations, they found that the Hepatitis C virus and the body’s immune system get into a deadlock when the body is fighting the virus.