Breast cancer remains a significant challenge, particularly in aggressive forms like triple-negative breast cancer (TNBC). This is a type of breast cancer where the tumour cells lack hormonal receptors, like estrogen receptors. This means that common breast cancer treatments targeting these receptors are not effective against TNBC, making it more challenging to treat and prone to spreading. Scientists are constantly searching for new ways to target the underlying mechanisms that allow these cancer cells to grow and spread unchecked. 

Topoisomerase

Bengaluru
28 Nov 2019

Our genetic material is a big molecule of DNA or deoxyribonucleic acid, whose structure is a double-stranded wound-up helix. It contains specific instructions that run a living cell, and these instructions are written on the strands. When cells divide, the DNA replicates too. In this process, the contents of the strands are read and copied carefully by unwinding the strands. But that's not as simple!