As cancer, a deadly disease, evolves, our fight against it does so too. Today, there are multiple therapies and drugs available that fight different types of cancer. Now, researchers have added a new drug called Disarib to this list that acts against a particular protein called BCL2. By killing cells that overproduce this protein, the researchers claim that Disarib can act effectively against most types of cancers. A first kind of its drug made completely in India, Disarib heralds a new breakthrough in Indian pharmaceutical research.

An education in science is a cherished dream for many. Unfortunately, it’s almost always limited to a few areas of study like engineering, medicine or dentistry. Thanks to the numerous avenues today, education in science has better career opportunities than ever, leaping beyond these traditional fields. So, what options does one have in the realm of science education? Here is a small effort to demystify the science education scene in the country.

Though our fight against tuberculosis has a long history, we have not been able to wipe off this bacterial infection from the face of the planet. Even to this day, there are numerous studies all over the world that are trying to find the ‘best’ drug against this killer disease. In a new approach to fight tuberculosis, a recent study has now shone some light on how our body fights Mycobacterium, the causative bacteria of TB. Understanding this mechanism, the researchers say, could open up new vaccines and drugs against TB and help us win the seemingly never ending battle. 

Technology has revolutionized almost every aspect of our lives - from healthcare to doing business. The field of meteorology is not far behind. In a recent study, scientists have leveraged the computing power of a new series of processors from Intel, to improve existing climate models and simulations. The new models, the researchers claim, have better accuracy and increased speeds and also free up meteorologists from the hassles of computer science.

Today is World Bicycle Day, a day celebrated to commemorate the joy of cycling. In a country like Netherlands, almost every person owns a cycle, and 99.1% are cyclists! But a city like Bengaluru -- almost thrice as big  and with 12 times more population -- loses hands down to Amsterdam, in citizens choosing to cycle. Why is that so? And what can be done to make people here fall in love with their bikes? The Research Matters team caught up with Prof. Ashish Verma, an Associate Professor at the Department of Civil Engineering, at the Indian Institute of Science (IISc), Bengaluru. 

The public transport system of Bengaluru is plagued by delays and inefficiencies that have resulted in huge losses to BMTC, the operator, and lack of quality services to the common people. Now, scientists from the Indian Institute of Science have proposed a new model of transport that aims to increase bus efficiency, reduce or eliminate delays and save money for both the transport corporation and its users - the people. The new model, researchers claim, could be a win-win situation for both and could revive the appeal of public transportation. 

Several studies in the recent years have focused on the health hazards of chemicals and pesticides used by farmers to protect their crops and improve their yields. Among the cocktail of poison, a controversial herbicide paraquat dichloride, marketed as Gramoxone, is infamous for its link to  accidental poisoning and suicides. Now, researchers have developed a new sensor using nanotechnology that not only detects paraquat, but also estimates its amount. This innovation can help save many innocent lives that grow our food.

Vitamin C, present is citrus fruits like lemons and oranges, is known to boost immunity and prevent our body from bacterial infections. But how does it do it? A new study by researchers from the Indian Institute of Science has now elucidated the mechanism behind why Vitamin C inhibits bacterial infections. This research also opens up possibilities for using Vitamin C in various therapeutic applications.

Graphene, also called a “wonder material” is increasingly being used in the field of electronics due to its lightweight and electrical properties. Now, researchers at the Indian Institute of Science, Bangalore, have identified a potential drawback in graphene transistors that have metal contact leads. The metal atoms in the contacts react with graphene atoms, creating an unwanted disturbance or noise in the electronic circuit. This discovery may have major implications on using graphene for futuristic electronic applications.  

In a pathbreaking research on anencephaly, a fatal birth defect where a baby is born without a major part of the brain and the skull, researchers from IISc and BMCRI have identified a genetic mutation that is responsible behind this condition. Technically called Tripartite Motif Containing 36 (TRIM36), this gene is responsible for the development of the nerve cells in a foetus. A modification to this, the scientists say, is to be blamed for anencephaly.