Researchers from the Indian Institute of Science (IISc), Bengaluru study how a protein called lysozyme, an integral component of our immune system, causes persistent nerve pain during nerve injury.

The impacts of climate change on coastal areas are severe than inland as they are vulnerable to flooding and extreme weather phenomena like cyclones, tornadoes etc. As the climate crisis deepens, a quarter of India's population, who live along the coasts, have another issue to worry about – availability of freshwater. Due to unchecked pumping of groundwater for daily use and rainfall variation, freshwater sources are being depleted. Besides, saltwater from the sea is unwittingly finding its way into local aquifers through a process called seawater intrusion. Although many independent studies, conducted at different locations, have observed depletion in freshwater sources along India's coasts, there is no comprehensive study yet. Now, researchers at Anna University, Chennai, have tried to address the extent of seawater intrusion in the Indian coastal regions in a study published in journal Environmental Science and Pollution Research. The study was funded by the National Centre for Earth Sciences Studies, Earth System Science Organisation, and the Ministry of Earth Sciences.

In a recent study, researchers from Pune's Agharkar Research Institute and Savitribai Phule University, and China's Zhejiang University have turned their attention towards Xyrids to gain a holistic understanding of the evolution of pipeworts.

In a recent study, Dr Sachdev and an international team of researchers have shown that India’s mortality rate due to severe acute malnutrition is a fraction of the WHO estimates. This study is published in the journal PLOS Medicine.

Several interacting molecular and biochemical processes are vital to establishing cell polarity. In a recent study, researchers at the Indian Institute of Science, Bengaluru, studied some of these signals in the centrosome—an organelle in the cell responsible for cellular organisation—of a single-cell embryo.

As Newton’s famous quote, “standing on the shoulders of giants”, this year, science has made considerable advances, building on many feats achieved in the past years. New discoveries, insights and inventions in the areas of astronomy, biology, medicine, paleontology and physics marked the year. Here is a selected pick of ten such breakthroughs in science witnessed in 2019.

While looking forward to 2020, the editorial team at Research Matters looks back on some of the interesting stories that we published during 2019. There were many interesting ones ranging from the first photograph of a black hole to air pollution in Delhi to using vibrations for painless injections. Here is a list to highlight India's year in science during 2019. This is in no way ranked and the order is just incidental.

2019 was an exciting year for science as ever. We have collated the top ten stories that was popular on Research Matters in 2019. These were the ones that garnered most views because of readers like you. We would like to thank you for patronage and look forward to your support in the years to come.

In a recent study, published in the journal Ecosphere, researchers from Columbia University, USA, and Nature Conservation Foundation, Mysore, have assessed the effects of active restoration in fragmented rainforests of the Western Ghats.

The Pradhan Mantri Ujjwala Yojna (PMUY) proved to be very attractive and has reached 80 million low-income families across the country. However, can we call it successful merely based on the number of people it has covered? A study, published by researchers from Canada, Austria, and the USA, compared the enrolment for the Ujjwala program and the trend of LPG consumption in rural Karnataka and found that although the scheme was successful in delivering its promises, it's success has been a topic of national debate.