Human Immunodeficiency Virus (HIV) infections are one of the most severe public health problems in India, with approximately 21 lakh HIV infected people reported in 2017. Sex workers, men who have sex with men, transgender people, and people who inject drugs are at a higher risk of contracting the virus. Scientists across the world are exploring the possibility of a drug that can be taken daily to keep HIV infections at bay, which could help in reducing the spread of the disease and an overall prevalence, besides acting as a preventive measure for those under high risk. In a recent study, published in the journal Clinical Infectious Disease, researchers evaluate if such a drug can act as a preventive measure in a developing country like India.