The whole world is struggling with the problem of antibiotic resistance developed by disease causing organisms. The epidemic of Tuberculosis especially plagues countries like India. In their recent research scientists from the Central University, Punjab have identified a new target drug to beat the bacteria’s defense against antibiotics.
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From their first appearance on the academic scene as a tool for dissection to making it into mainstream medicine and cosmetics in the recent years, microneedles have an array of applications. Dr.Venuganti and a team of researchers from the Birla Institute of Technology and Science, Hyderabad and the US Food and Drug Administration, recount the journey microneedles have made through the years and the range of possible applications in the future.
Across many countries in the world, people from an economically backward background struggle to get adequate medical care. As a part of its Sustainability and development goals for 2015 the United Nations has declared ensuring “healthy lives and promote well-being for all at all ages”. This target of Universal Health Coverage (UHC) aims to ensure accessibility to quality health care services by the year 2030. With 13 years to go, an international team of scientists explores how this goal can be achieved in five South Asian countries.
Malaria, the biggest killer of all time, has a long association with humans. As we develop new strategies to combat the fatal disease, the parasite causing the disease gets stronger than ever. In this seemingly never-ending tussle, who ultimately wins the battle? The judgement, it seems, is not an easy one! On World Malaria Day, here is a brief insight into the details of this deadly disease.
Technology has revolutionised medicine in the past century. We now have imaging methodologies like X-rays, Computed Tomography (CT) scans and Magnetic Resonance Imaging (MRI) allowing us a look inside the body without cutting it open. Nanotechnology seems poised to write the next chapter of this revolution, with various applications in biomedical imaging, diagnosis and effective treatment of diseases. In yet another advancement in this direction, an interdisciplinary team of scientists from Materials Engineering Department and Department of Microbiology and Cell Biology at the Indian Institute of Science (IISc), Bangalore, have synthesised iron nanoparticles without any oxide cover that could be used to enhance the sensitivity of MRI by producing images with better contrast. They have also demonstrated the potential application of this research in the targeted delivery of medicines and other biological molecules to specific organs in the body.
Tuberculosis (TB) is one of the deadliest infectious diseases in the world, affecting 9.6 million people worldwide in 2015, of which 2.2 million were in India. Although tuberculosis is curable through antibiotics, the increasing prevalence of multi-drug resistant forms of TB has become a major concern. A new study from the lab of Prof. Krishnamurthy Natarajan at the University of Delhi, uncovers new mechanisms through which the TB microbe interacts with cells of the host immune system, hijacking their function and preventing them from doing their job properly. The findings of the study point to new ways of treating patients afflicted with drug-resistant TB.
In a collaborative study between the Indian Institute of Science (IISc), Bangalore, and the University of Twente, The Netherlands, researchers have designed a new algorithm for image recovery in Photoacoustic Tomography (PAT). PAT is an important non-invasive biomedical imaging technique where the optical contrast rendered by laser beams and the superior resolution of ultrasound waves are used to study biological tissues. The new algorithm works better with higher accuracy as compared to the conventional ones in use today.
Over the last several decades, antibiotics have played a critical role in fighting infectious diseases caused by bacteria and other microbes. However, blatant misuse and overuse of these drugs has resulted in the bacteria becoming resistant to a wide range of antibiotics where it changes itself to eliminate the action of the antibiotics and thus renders the drug useless. A recent work by researchers at the Indian Institute of Science, Bangalore and the Bose Institute, Kolkata, has addressed the challenge of antibiotic resistance using nanotechnology.
As Alfred Nobel quoted in his will, “For the greatest benefit to mankind”, the Nobel Assembly at Karolinska Institute, Sweden, has opened this year’s list by announcing the winner for Physiology or Medicine on Monday. Yoshinori Ohsumi from Japan has bagged the 2016 Nobel Prize in Physiology/Medicine for his “Discoveries of mechanism for Autophagy”.