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DNA

Bengaluru | Nov 28, 2019
Close Connections: Topoisomerase enzymes, which alleviate DNA stress, connect with critical cell functions

Our genetic material is a big molecule of DNA or deoxyribonucleic acid, whose structure is a double-stranded wound-up helix. It contains specific instructions that run a living cell, and these instructions are written on the strands. When cells divide, the DNA replicates too. In this process, the contents of the strands are read and copied carefully by unwinding the strands. But that's not as simple!

General, Science, Technology, Deep-dive
Hyderabad | Aug 22, 2019
 Where are those skeletons, tumbling out from the mysterious Roopkund lake, from?

Roopkund is a small Himalayan glacial lake in Uttarakhand, situated at an altitude of about 16,470 feet. With its breathtaking scenery, it is a popular trekking destination. However, there is more to this mysterious lake—hundreds of ancient human skeletons lie scattered here, earning it the name ‘skeletons lake’. In a recently published decade-long study, an international team of researchers seem to have traced the origins of these puzzling skeletons.

General, Science, Deep-dive
Bengaluru | Jan 2, 2019

A long-standing mystery in the evolution of life seems to be solved in a study by researchers from the Indian Institute of Science, Bengaluru, Cedars-Sinai Medical Center, USA, and the Cleveland Clinic Foundation, USA. The study, published in The Journal of Biological Chemistry, provides a convincing explanation about the fusion of two genes in an ancestor of today’s animals, about a billion years ago.

General, Science, Technology, Health, News
Bengaluru | Dec 12, 2018
Photo: Prof Ganesh Nagaraju via IISc

Dr Ganesh Nagaraju, Associate Professor at the Department of Biochemistry, Indian Institute of Science, Bengaluru, has been awarded the 2018 Shanti Swarup Bhatnagar Prize in Biological Sciences for his work on DNA repair, chromosome instability, genetic diseases and cancer.

General, Science, News
Bengaluru | Sep 21, 2018

Scientists are always on the lookout for novel chemical compounds with medicinal properties to fight many of the diseases we know. In one such effort, researchers from the Aligarh Muslim University, Uttar Pradesh, and their collaborators have developed three compounds with steroids and pyrimidines with remarkable biological applications. The results of the study are published in the International Journal of Biological Macromolecules.

General, Science, Health
Bengaluru | Sep 6, 2018
Photo: Vssun/ CC BY-SA 3.0

Study from the Ashoka Trust from Research in Ecology and the Environment details the importance of a global standard to curb the adulteration of herbal medicines.

General, Science, Health, Deep-dive
Bengaluru | Jul 19, 2018

Haven’t we all heard about DNA, the genetic material that makes who we are? Short for Deoxyribonucleic acid, the DNA is made of two chains that coil around each other forming the double helix structure as we know it today. Although Friedrich Miescher first isolated the DNA molecule in 1869, it was not until 1953 that we understood its structure. Two scientists, James Watson and Francis Crick, are well-known for showing us the double-helix structure of the DNA.

General, Science, News, Events
Thiruvananthapuram | Jun 5, 2018

Researchers from Indian Institute of Science Education and Research (IISER) Thiruvananthapuram, Kerala and Institute of Microbial Technology, Chandigarh have developed a novel method to synthesize 2 dimensional nanosheets decorated with DNA molecule. The design strategy allows for an ultra dense array of DNA molecules to be grown on 2 D crystalline nanosheets.

General, Science, Technology, News
Bengaluru | Dec 29, 2017

Scientists from Council of Scientific and Industrial Research – Indian Institute of Toxicology Research (CSIR-IITR) and Amity University, Uttar Pradesh have been studying the harmful effects of Zinc Oxide nanoparticles (ZnO NPs) on living tissue and genes in mice, and their study reveals a potential threat lurking, if increasing use of such nanoparticles is not addressed soon.

General, Science, Health
Dec 26, 2017
Infographic : Purabi Deshpande / Research Matters

Dr. Lalji Singh was born in the small village of Kalwari in Jaunpur district of Uttar Pradesh on 5th July 1947, to a farmer and head of village, Suryanarayan Singh. With no higher education facilities in his village, Lalji strived for an education early on, travelling to a nearby village to complete his schooling and joining the reputed Banaras Hindu University. After completing his undergraduate and postgraduate degrees from BHU, Lalji was admitted for his PhD in the same university.

General, Science
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