Responsible for 1.5 to 5 million deaths per year, around the world, Diabetes mellitus is a very serious disease. India is considered the diabetes capital of the world with as many as 50 million people suffering from type 2 diabetes. This World Diabetes Day, the Research Matters team caught up with Dr. Milind Watve, a professor at the Indian Institute of Science Education and Research Pune and an expert in the field, to find out about the new insights into how better to treat the disease.
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An important aspect in the life of social animals is to gather information from others in their group. Young members of the group also learn how to forage, feed, evade predators and attract mating partners from older members. Scientists from Indian Institute of Science Education and Research, Kolkata explore how Zebra fish, that live in shoals of 20 individuals in the wild, learn informations from their partners in a laboratory environment.
Our nervous system is one of the most complex systems in our body. It consists of billions of nerve cells that work in tandem and processes billions and billions of calculations per second. But how are these neurons formed in our body and what controls them? In a recent study, scientists have discovered a molecule that they claim controls the mechanism in which nerve cells are formed. This study may help uncover some of the key aspects that can treat neurodegenerative disorders like Parkinson’s.
Escherichia coli, a poster boy for microbiology research and the notorious bacteria that causes stomach infections, might soon be an unusual source of inspiration for us, humans, for learning how to handle stress! A new study by scientists at the Indian Institute of Science, Education and Research (IISER) Pune, has revealed, for the first time, that E. coli cells become more sturdy and fit when exposed to unpredictably fluctuating environments containing high levels of salts or chemicals, or having extreme pH values. Led by Prof. Sutirth Dey, the study aims to investigate the evolution of fitness and the costs incurred by the bacteria in this process.
Diabetes mellitus is one of the prevalent non-communicable diseases in the world, with India being infamously called the diabetes capital. A report by World Health Organization states that the number of diabetics has quadrupled since 1980 to 422 million adults globally. India has witnessed a dramatic rise in its diabetic population from 11.9 million in 1980 to 69.2 million in 2015. This alarming worldwide rise in the visibility of diabetes has prompted urgent research and intervention to alleviate its potentially catastrophic consequences. Prof. Milind Watve’s lab at the Indian Institute of Science, Education and Research (IISER), Pune, is adding a new dimension to this research by studying the underlying pathogenesis of diseases like diabetes from an evolutionary perspective.
How many tropical diseases do you know of? Malaria, dengue and sleeping sickness immediately come to mind. Maybe leprosy, if you think hard enough. But, many of us may not have heard of cutaneous leishmaniasis, a less dangerous but much more prevalent cousin of kala azar or black fever. Cutaneous Leishmaniasis (CL) is caused by the protozoan Leishmania parasites which are transmitted by the bite of infected female sandflies. A team of researchers led by Dr. Shailza Singh from the National Centre for Cell Science (NCCS), Pune have been studying this disease extensively and have now discovered a new lead compound to help combat this neglected tropical disease. Dr. Sudipta Basu and his team from Indian Institute of Science Education and Research (IISER), Pune have co-authored this work.