The nucleus of the cell holds our genetic material and is a vital part of our cell. Apart from what they carry, how they look also plays a crucial role in diagnosing many diseases. In a recent study, researchers at the Indian Institute of Science (IISc), Bengaluru, have developed a mechanical model to quantify the shape of the nucleus and predict the biochemistry within a cell. They have used this model to show how Hepatitis C virus changes the nuclear mechanics of cells affected by it. This study is published in the Biophysical Journal.
Two new studies from the Indian Institute of Bombay (IIT Bombay), Mumbai, show the importance of defects in the arrangement of atoms in a crystal, called dislocations, in shaping the physical properties of metallic alloys.