Researchers at IISc find a way to dismantle bacterial biofilms, enhancing antibiotic effectiveness.

Researchers have used modified sugars to hamper the development of cell wall in disease-causing bacteria

Many lifesaving medical devices such as urinary catheters, pacemakers, intrauterine devices and voice prosthesis, which are usually inserted into some part of the body, are plagued by a common problem – ‘bacterial biofilms’. These ‘biofilms’ grow on the surfaces of these devices and may cause infections. They are harder to treat than individual bacteria and need about 1000 – 10000 times stronger dose of antibiotics. But this may no longer be the case, as a group of scientists led by Prof. Dipshikha Chakravortty and Prof. Jagadeesh Gopalan from the Indian Institute of Science, Bangalore, have found a novel method to fight biofilm infections.