In a recent study, researchers at the Indian Institute of Science, Bengaluru, have described how the pathogenic bacteria Salmonella, which causes a range of diseases from diarrhoea to typhoid, escapes from our immune system. The findings of this study, funded by the Department of Biotechnology and the Department of Atomic Energy, have been published in the journal PLoS Pathogens.
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Researchers from CMC Vellore, AIIMS, TN Medical College & BYLN Hospital, and THSTI, throw some light on the recent trend of the diseases typhoid and paratyphoid fever.
Microbes live with us and among us. They occupy portions of our body and help us perform many daily bodily functions. Scientists call these microbes that live in our body the Human microbiome. In their latest research, scientists from the Centre for DNA Fingerprinting and Diagnostics and Max Planck Institute for Evolutionary Anthropology, Germany, study the salivary microbiome in Indians.
Foodborne diseases, caused by Salmonella, are responsible for 1 in 10 illnesses globally. Treating Salmonella infections using traditional antibiotics is turning to be a challenge because of the development of drug resistant strains. Now, a new study at IISc has developed nanotechnology based nanocarries using silica that can deliver very small dosage of antibiotics to the affected cells, thus hitting the right target. Using laboratory experiments, the researchers found that these nanocarries performed much better than conventional antibiotics in all stages of the infection. The design of these nanocarries are generic, and can be used for delivering different antibiotics, they claim.