The success rate of the ambitious Revised National Tuberculosis Control Programme (RNTCP), driven by the Government of India, is appaling, reports a study.
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This study, by researchers from Hungary, India, France and the USA, explored the potential of some new chemical compounds as therapeutic agents against tuberculosis. Such compounds represent new possibilities for further anti-TB drug development.
A collaborative study by researchers from Punjab University, Indian Institute of Technology (IIT) Delhi, Banasthali University, TERI University and the Jawaharlal Nehru University has identified how a particular gene in Mycobacterium tuberculosis, the causative agent of tuberculosis (TB), mutates to avoid the action of antibiotics.
Scientists from the Indian Institute of Science, Bangalore, study what effect tuberculosis has on the immune system of our body.
In a novel study, researchers from the Indian Institute of Technology, Bombay, test how oxidative stress induced by a combination of drugs can help fight drug resistant strains of Tuberculosis.
A new study conducted by Pallavi Sinha and group from Institute of Medical Sciences, Banaras Hindu University and Boston Medical Centre has concluded that behavioral factors, like alcohol consumption and smoking, and clinical factors, like previous anti tubercular treatment, increases the risk of multi-drug resistant TB (MDR-TB).
Tuberculosis(TB) has claimed 1.8 million human lives globally according to World Health Organization, in 2015. Despite Bacillus Calmette-Guerin (BCG) vaccine, the only available vaccine for TB, currently one-third of the world is latently infected with TB due to the incompetence of BCG in adults against Mycobacterium tuberculosis, the bacteria responsible for TB.
Scientists from the Central University of Gujarat (CUG), Gandhinagar, use computers to design the most efficient drug against TB. They apply pharmacophore modelling approach to understand the interactions between proteins found in Mycobacterium tuberculosis (Mtb) and the compounds which can suppress the bacteria.
The whole world is struggling with the problem of antibiotic resistance developed by disease causing organisms. The epidemic of Tuberculosis especially plagues countries like India. In their recent research scientists from the Central University, Punjab have identified a new target drug to beat the bacteria’s defense against antibiotics.
A new study at IISc looks to uncover the secret behind the development of drug resistance in TB causing bacteria by testing the efficacy of various commonly available antibiotics. The researchers have found that a combination of commonly available antibiotics along with Augmentin, fights the development of resistance among TB bacteria. This study might throw light on developing new class of drugs that can help contain the spread of deadly tuberculosis, claim the researchers.