Voluntary movements, like lifting your hand to wave, are executed through precise coordination between different brain areas. Sometimes, due to the loss of neurons in the brain, some individuals cannot coordinate such voluntary movements and are said to be suffering from a condition called ataxia. A type of ataxia, known as the spinocerebellar ataxia, involves the loss of neurons from the spinal cord and cerebellum. These brain areas are responsible for controlling movement and balance.

Autophagy, or self-eating, is a process where cells in our body devour some of the cell components to replenish their nutrient supply during severe shortage.  This process, though sounds gruesome, is essential for our survival and any defect in this mechanism could lead to neurodegenerative disorders like Parkinson’s disease. Several research, inspired by Nobel Laureate Prof. Yoshinori Ohsumi’s work on autophagy, has now uncovered new dimensions on our understanding of how cells function.